The Science of Rooibos: What Human Research Actually Shows

Rooibos has attracted scientific interest for its polyphenols, antioxidant activity and possible relationship with cardiovascular and metabolic markers. Here is what human research has actually found so far, and where the evidence still has limits.

Rooibos leaves and brewed rooibos tea representing scientific research into rooibos

Rooibos has been enjoyed as a South African herbal infusion for generations, but over the past few decades it has also become the subject of growing scientific interest.

Researchers have investigated the plant, Aspalathus linearis, because it contains a range of naturally occurring polyphenols and other compounds that may influence antioxidant activity and other biological processes.

That does not mean every claim made about rooibos has been proven. Much of the research remains laboratory or animal based, and the number of larger, long-term human trials is still relatively limited.

So what has actually been studied in people?

Why Scientists Are Interested in Rooibos

One of the main areas of rooibos research is its polyphenol content.

Polyphenols are naturally occurring plant compounds. Rooibos contains several of them, including compounds such as aspalathin and nothofagin, which have attracted attention because of their antioxidant activity.

A 2023 review of rooibos health research mapped decades of published work and found that researchers have investigated the plant in areas including oxidative stress, inflammation, cardiovascular health and metabolic health. The Science of Rooibos

The review itself does not prove that rooibos prevents or treats any of those conditions. It shows where scientific attention has been focused.

That distinction matters.

Scientific interest tells us a subject is worth studying. It does not automatically turn an interesting finding into a health claim.

What Human Research Says About Antioxidant Activity

Antioxidant activity is one of the most widely studied characteristics of rooibos.

Antioxidants interact with reactive molecules involved in oxidative processes in the body. Laboratory research has shown antioxidant activity in several compounds naturally present in rooibos. The Science of Rooibos

Researchers have also looked at what happens after people actually drink it.

One crossover study involved 15 healthy volunteers who consumed fermented rooibos, unfermented green rooibos or water.

Both rooibos preparations produced a measurable increase in plasma antioxidant capacity after consumption. The Science of Rooibos

The published study reported increases following both fermented and unfermented rooibos, although the response differed between the two preparations. ScienceDirect

That gives us useful evidence that compounds in rooibos can have measurable effects after consumption.

It does not mean that drinking rooibos has been proven to prevent disease.

What Cardiovascular Research Has Examined

Rooibos has also been investigated in relation to cardiovascular biomarkers.

In one study led by Professor Jeanine Marnewick at Cape Peninsula University of Technology, 40 adults considered at risk for cardiovascular disease consumed six cups of fermented rooibos each day for six weeks. The Science of Rooibos

Researchers measured a range of biochemical markers, including oxidative stress indicators and blood lipids. The study reported changes in several of these measurements after the rooibos intervention. PubMed

Another study looked at angiotensin-converting enzyme, usually shortened to ACE.

Seventeen healthy volunteers consumed a single 400 ml serving of rooibos. Researchers recorded temporary inhibition of ACE activity at 30 and 60 minutes after consumption. The Science of Rooibos PubMed

Again, the important word is temporary.

This does not establish rooibos as a treatment for high blood pressure or cardiovascular disease. The study measured a biological response under specific experimental conditions.

That is very different from demonstrating a clinical treatment effect.

Can Rooibos Compounds Be Absorbed by the Body?

Another useful question is whether the compounds researchers identify in rooibos simply remain in the cup, or whether some of them can actually be detected after consumption.

A crossover study involving 12 healthy men investigated beverages made from unfermented rooibos.

Researchers identified metabolites associated with the rooibos compounds aspalathin and nothofagin in blood and urine after participants consumed the rooibos preparations. The Science of Rooibos

The published study identified several metabolites and detected some rooibos-derived flavonoids following consumption. PubMed

That provides evidence that at least some rooibos polyphenols can be absorbed and metabolised by the human body.

It still does not tell us that absorption automatically results in a particular long-term health outcome.

Red Rooibos and Green Rooibos Are the Same Plant

Red rooibos and green rooibos are not different species.

Both come from Aspalathus linearis.

The difference is mainly what happens after harvesting.

Traditional red rooibos undergoes oxidation during processing. This contributes to the familiar reddish colour and smooth, naturally sweet flavour associated with conventional rooibos.

Green rooibos is processed in a way that limits oxidation.

That difference in processing also changes the polyphenol profile of the finished product. The Science of Rooibos

Research has found differences between fermented and unfermented rooibos, including differences in antioxidant composition.

What the current human evidence does not establish is that one should be described as clinically healthier than the other. Both forms have demonstrated antioxidant activity in human research. The Science of Rooibos

So the more useful distinction for most tea drinkers is not simply “healthy versus healthier.”

It is that different processing produces different chemical profiles, colour and flavour characteristics.

What Does the Science of Rooibos Actually Tell Us?

There is genuine scientific interest in rooibos.

Human studies have investigated antioxidant activity, oxidative stress markers, cardiovascular biomarkers and the absorption of rooibos polyphenols. Broader research has also explored inflammation, glucose metabolism and metabolic health. The Science of Rooibos

But the evidence needs to be kept in perspective.

Many published rooibos studies are still based on laboratory or animal models, while the body of larger and longer-term human clinical research remains comparatively limited. The Science of Rooibos

That is why we prefer the simpler conclusion.

Rooibos is a distinctive South African herbal beverage with an interesting and growing body of research behind it.

The science is worth following.

It does not need to be exaggerated.

Research Referenced in This Article

Abdul, N.S. & Marnewick, J.L. (2023)
What has been the focus of Rooibos health research? A bibliometric overview.
Journal of Herbal Medicine, 37, 100615. DOI: 10.1016/j.hermed.2022.100615. The Science of Rooibos ScienceDirect

Marnewick, J.L. et al. (2011)
Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease.
Journal of Ethnopharmacology, 133(1), 46-52. DOI: 10.1016/j.jep.2010.08.061. The Science of Rooibos PubMed

Villaño, D. et al. (2010)
Unfermented and fermented rooibos teas increase plasma total antioxidant capacity in healthy humans.
Food Chemistry, 123, 679-683. DOI: 10.1016/j.foodchem.2010.05.032. The Science of Rooibos ScienceDirect

Breiter, T. et al. (2011)
Bioavailability and antioxidant potential of rooibos flavonoids in humans following the consumption of different rooibos formulations.
Food Chemistry, 128(2), 338-347. DOI: 10.1016/j.foodchem.2011.03.029. The Science of Rooibos PubMed

Persson, I.A.L. et al. (2010)
Effects of green tea, black tea and Rooibos tea on angiotensin-converting enzyme and nitric oxide in healthy volunteers.
Public Health Nutrition. DOI: 10.1017/S1368980010000170. The Science of Rooibos PubMed

Scientific information in this article is provided for educational purposes only. Rooibos is a food and beverage product and is not intended to diagnose, treat, cure or prevent disease. Research findings discussed above relate to the specific study conditions and populations examined. The Science of Rooibos

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